Learn More
Tamoxifen, 98%
Product Code. 15475719
Brand: Thermo Scientific Alfa Aesar J63509.03
Description
Inhibitor of protein kinase C and induces apoptosis in cancer cells. It is utilized in the study on lipopolysaccharide (LPS)-induced microglial activation to know its effect.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Tamoxifen is a tertiary aminobenzene that acts by competitively binding and antagonizing estrogen receptors to reduce DNA synthesis
- When estradiol cannot bind estrogen receptors, the DNA response element is not activated
- Tamoxifen upregulates the production of TGFb and slows tumor growth
- Tamoxifen inhibits the production of IGF-1, a stimulator of tumor growth
Application
- Tamoxifen may be useful in the study of tumorigenesis, growth, and inflammation
- It is suitable for in vitro experiments
Specifications
Specifications
| Color | White |
| Quantity | 1 g |
| Merck Index | 14,9048 |
| Solubility Information | Insoluble in water; Soluble in methanol,ethanol,propanol or propylene glycol;Soluble in dimethyl sulfoxide,dichloromethane and ethanol; Insoluble in water. |
| Formula Weight | 371.52 |
| Percent Purity | 98% |
| Physical Form | Powder |
| Chemical Name or Material | Tamoxifen |
Sicherheit und Handhabung
- Tamoxifen
- Danger
- Acute toxicity Category 4
- Carcinogenicity Category 1A
- Reproductive toxicity on or via lactation
- Reproductive toxicity Category 1A
- H302-Harmful if swallowed.
- H350-May cause cancer.
- H360FD-May damage fertility. May damage the unborn child.
- H362-May cause harm to breast-fed children.
- P201-Obtain special instructions before use.
- P263-Avoid contact during pregnancy/while nursing.
- P264-Wash face, hands and anyexposed skin thoroughly after handling.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
- MIXTURE LIST-Contains : Tamoxifen
RUO – Research Use Only
Bitte geben Sie uns Ihr Feedback zu den Produktinhalten, indem Sie das folgende Formular ausfüllen.