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Thermo Scientific™ Tango™ EDG6-bla U2OS Cells

Product Code. 10243798
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Quantity:
2 x 106 Cells
Unit Size:
Pack of 2
This item is not returnable. View return policy

Product Code. 10243798

Brand: Thermo Scientific™ K1622B

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Description

The Tango™ EDG6-bla U2OS cells contain the human Endothelial Differentiation, Lysophosphatidic Acid G-protein-coupled Receptor, 6 (EDG6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

The Tango™ EDG6-bla U2OS cells contain the human Endothelial Differentiation, Lysophosphatidic Acid G-protein-coupled Receptor, 6 (EDG6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ EDG6-bla U2OS cells cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ EDG6-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_003775.1
Cell State Dividing Cells
Content And Storage Store in liquid nitrogen immediately, LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• Tango™ EDG6-bla U2OS cells
• Tango™ EDG6-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ EDG6-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method Fluorescence
Gene Symbol EDG6
Quantity 2 x 106 Cells
Reporter Gene BLA (Beta-Lactamase)
Type U2OS Cell
Cell Line U2OS
System Type Tango™
Druggable Target GPCR
Target GPCRs
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For Research Use Only. Not for use in diagnostic procedures.

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