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Invitrogen™ TAOK2 Polyclonal Antibody
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Product Code. 16349364
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Quantity:
100 μL
Unit Size:
100µL
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16349364 100 μL 100µL
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Product Code. 16349364 Supplier Invitrogen™ Supplier No. PA582401

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SISASSQSSS VNSLADASDN EEEEEEEEEE EEEEEGPEAR EMAMMQEGEH TVTSHSSIIH RLPGSDNLYD DPYQPEITPS PLQPPAAPAP TSTTSSARRR AYCRNRD Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 94%.

TAOK2 (TAO1) is a serine/threonine kinase that may be an important regulator of the stress-responsive p38 MAP kinase pathway. In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TAOK2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TAOK2
Gene Accession No. Q9UL54
Gene Alias 1110033K02Rik; B230344N16; hKFC-C; Kiaa0881; Kinase from chicken homolog C; MAP3K17; mKIAA0881; prostate derived STE20-like kinase PSK; prostate-derived STE20-like kinase 1; prostate-derived sterile 20-like kinase 1; PSK; PSK1; PSK-1; PSK1-BETA; serine/threonine protein kinase TAO2; serine/threonine-protein kinase TAO2; serine-threonine kinase; tao; TAO kinase 2; TAO kinase 2TAO kinase 2; TAO1; TAO2; TAOK2; Thousand and one amino acid protein 2; thousand and one amino acid protein kinase 2; UNQ2971/PRO7431
Gene Symbols TAOK2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TAOK2. Recombinant protein control fragment (Product #RP-89791).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9344
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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