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Invitrogen™ TAPP1 Monoclonal Antibody (376409)
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Product Code. 15503812
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Quantity:
100 μg
Unit Size:
100µg
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15503812 100 μg 100µg
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Product Code. 15503812 Supplier Invitrogen™ Supplier No. MA524117

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Description

Rat Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

Phosphatidylinositol-4,5-bisphosphate 3-phosphatase adapter protein 1 (TAPP1) is a gene located on chromosome 1q25.2, encoding a protein involved in intracellular signaling pathways that regulate cellular processes such as proliferation, survival, and migration. TAPP1 is characterized by containing pleckstrin homology (PH) domains, which allow it to bind specifically to phosphoinositide lipids, particularly phosphatidylinositol (3,4) bisphosphate. This interaction is crucial for the localization of TAPP1 to cell membranes where it can act as an adaptor protein, modulating the activity of downstream signaling molecules and pathways. TAPP1 is expressed in various tissues and plays a role in immune cell function, influencing processes like cell motility and cytoskeletal dynamics. Research into TAPP1 focuses on its role in immune regulation and signaling, with implications for understanding its function in disease contexts such as cancer and autoimmune disorders where phosphoinositide signaling is disrupted.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TAPP1
Applications Western Blot
Classification Monoclonal
Clone 376409
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene PLEKHA1
Gene Accession No. Q9HB21
Gene Alias AA960558; C920009D07Rik; PH domain-containing family A member 1; pleckstrin homology domain containing A1; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1; pleckstrin homology domain-containing family A member 1; pleckstrin homology domain-containing protein family A member 1; PLEKHA1; RGD1564153; tandem PH domain containing protein-1; tandem PH domain-containing protein 1; TAPP1; TAPP-1
Gene Symbols PLEKHA1
Host Species Rat
Immunogen E. coli-derived recombinant human TAPP1 Pro2-Val404.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 59338
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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