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TC E3 5031, Tocris Bioscience™
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Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

Brand:  Tocris Bioscience 6466/100

Encompass

Product Code. 15963091

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Description

Description

TC E3 5031 is a derivative of Thalidomide (Cat.No. 0652), commonly used as a precursor to PROTAC® that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with a carboxylic acid functional handle at a position known not to significantly affect binding to cereblon, for ready conjugation to a linker/target protein ligand.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Require a different derivative? Get in touch .

Specifications

Specifications

1061605-21-7
2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid
100 mg
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