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TCAP Mouse anti-Human, Clone: OTI3E7, lyophilized, TrueMAB™
Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
Specifications
Specifications
| Antigen | TCAP |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | OTI3E7 |
| Conjugate | Unconjugated |
| Formulation | PBS with 8% trehalose and no preservative; pH 7.3 |
| Gene | TCAP |
| Gene Accession No. | O15273 |
| Gene Alias | CMD1N, CMH25, LGMD2G, T-cap, TELE, telethonin |
| Gene Symbols | TCAP |
| Show More |
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