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Invitrogen™ DCAF12 Polyclonal Antibody
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Product Code. 17127553
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Quantity:
100 μL
Unit Size:
100µL
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17127553 100 μL 100µL
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Product Code. 17127553 Supplier Invitrogen™ Supplier No. PA5109619

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MARKVVSRKR KAPASPGAGS DAQGPQFGWD HSLHKRKRLP PVKRSLVYYL KNREVRLQNE TSYSRVLHGY AAQQLPSLLK EREFH.

Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DCAF12
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.75 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene DCAF12
Gene Accession No. Q5T6F0
Gene Alias 1500001L20Rik; 5830424K06Rik; AA420338; AI851081; cancer/testis antigen 102; centrosome-related protein TCC52; CT102; Dcaf12; DDB1 and CUL4 associated factor 12; DDB1- and CUL4-associated factor 12; Kiaa1892; LOC682812; similar to WD repeat domain 40A; TCC52; Testis cancer centrosome-related protein; WD repeat domain 40A; WD repeat-containing protein 40A; WDR40A
Gene Symbols DCAF12
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human DCAF12 (NP_056212.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25853, 682812
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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