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Invitrogen™ TCEB1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA546866
This item is not returnable.
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Description
Peptide sequence: AENETNEVNF REIPSHVLSK VCMYFTYKVR YTNSSTEIPE FPIAPEIALE Sequence homology: Dog: 100%; Human: 100%; Zebrafish: 100%.
TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Specifications
| TCEB1 | |
| Polyclonal | |
| Unconjugated | |
| ELOC | |
| 2610043E24Rik; 2610301I15Rik; AA407206; AI987979; AW049146; eloC; elongation factor SIII p15 subunit; elongin 15 kDa subunit; elongin C; elongin-C; RNA polymerase II transcription factor SIII subunit C; SIII; SIII p15; Stromal membrane-associated protein SMAP1B homolog; Tceb1; transcription elongation factor B (SIII), polypeptide 1; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); transcription elongation factor B polypeptide 1; transcription elongation factor B polypeptide 1; elongin-C; transcription elongation factor B subunit 1 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 6921 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| Q15369 | |
| ELOC | |
| Synthetic peptide directed towards the middle region of human TCEB1. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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