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Invitrogen™ TCF7 Monoclonal Antibody (G.452.9)
Rabbit Monoclonal Antibody
Brand: Invitrogen™ MA514972
This item is not returnable.
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Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with LEF1.
TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
Specifications
| TCF7 | |
| Monoclonal | |
| 163 μg/mL | |
| 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5 | |
| P36402, Q00417 | |
| TCF7 | |
| Synthetic peptide corresponding to a region surrounding Leu160 of human TCF1/TCF7 protein. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Immunoprecipitation, Western Blot, Immunocytochemistry | |
| G.452.9 | |
| Unconjugated | |
| TCF7 | |
| AI465550; HMG-box; OTTHUMP00000159390; OTTHUMP00000159391; T cell factor-1; T-cell factor 1; T-cell specific; T-cell-specific transcription factor 1; Tcf1; TCF-1; Tcf7; TCF-7; Transcription factor 7; transcription factor 7 (T-cell specific, HMG-box); transcription factor 7, T cell specific; transcription factor 7, T-cell specific | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 21414, 363595, 6932 | |
| -20°C | |
| Liquid |
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