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Invitrogen™ TCF7 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA578191

Product Code. 16366894

  • € 566.00 / 100µL

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Description

Description

Positive Control: HepG2, Jurkat Predicted Reactivity: Mouse (97%), Bovine (95%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TCF7
Polyclonal
Unconjugated
TCF7
AI465550; HMG-box; OTTHUMP00000159390; OTTHUMP00000159391; T cell factor-1; T-cell factor 1; T-cell specific; T-cell-specific transcription factor 1; Tcf1; TCF-1; Tcf7; TCF-7; Transcription factor 7; transcription factor 7 (T-cell specific, HMG-box); transcription factor 7, T cell specific; transcription factor 7, T-cell specific
Rabbit
Antigen affinity chromatography
RUO
21414, 363595, 6932
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
P36402, Q00417
TCF7
Recombinant protein encompassing a sequence within the center region of human TCF7. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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