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TCR beta Armenian Hamster, anti-Mouse, Unconjugated, Clone: H57-597, Proteintech
Armenian Hamster Monoclonal Antibody
Brand: Proteintech 65106-1-IG-100UG
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Description
T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
Specifications
| TCR beta | |
| Monoclonal | |
| 0.5 mg/mL | |
| Armenian Hamster | |
| Primary | |
| Mouse |
| Flow Cytometry | |
| H57-597 | |
| Unconjugated | |
| 100 μg | |
| 21577 | |
| Liquid |
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