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  6. Tenovin-6 Hydrochloride, MedChemExpress

Tenovin-6 Hydrochloride, MedChemExpress

Product Code. 16476786
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Product Code. 16476786

Brand: Medchem Express HY15510B

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Description

MedChemExpress Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH).

Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH).

Specifications

Chemical Name or Material Tenovin-6 Hydrochloride
Physical Form Solid
CAS 1011301-29-3
Color Yellow
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C25H35ClN4O2S
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : ≥ 49 mg/mL (99.78 mM)
SMILES O=C(NC(NC1=CC=C(NC(CCCCN(C)C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2.Cl
Molecular Weight (g/mol) 491.09
Formula Weight 491.09
Percent Purity 98.0%
Grade Research
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Research purposes only

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