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Invitrogen™ TFEB Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA596632
This item is not returnable.
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Description
Positive Samples: Raji, NIH/3T3, mouse spleen, mouse kidney, rat brain, rat spleen; Cellular Location: Cytoplasm, Nucleus.
The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
Specifications
| TFEB | |
| Polyclonal | |
| Unconjugated | |
| TFEB | |
| Alpha TCFEB; ALPHATFEB; BHLHE35; Class E basic helix-loop-helix protein 35; RP4-696P19.3; T-cell transcription factor EB; Tcfeb; Tfeb; Transcription factor EB | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 21425, 316214, 7942 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
| P19484, Q9R210 | |
| TFEB | |
| Recombinant protein (or fragment). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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