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TG Monoclonal Antibody (OTI8E6), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA804211
This item is not returnable.
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Description
Thyroglobulin (Tg) is a glycoprotein homodimer produced predomitly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.Specifications
| TG | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P01266 | |
| TG | |
| Human recombit protein fragment corresponding to amino acids 20-358 of human TG produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI8E6 | |
| Unconjugated | |
| TG | |
| AITD3, TGN | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 7038 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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