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TG Monoclonal Antibody (OTI8F6), TrueMAB™, OriGene

Product Code. 17563673
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100 μL
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30µL
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17563673 100 μL 100µL
17583673 30 μL 30µL
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Product Code. 17563673 Supplier Origene Technologies Supplier No. TA804215

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Description

Mouse Monoclonal Antibody

Thyroglobulin (Tg) is a glycoprotein homodimer produced predomitly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Specifications

Antigen TG
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI8F6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TG
Gene Accession No. P01266
Gene Alias AITD3, TGN
Gene Symbols TG
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 20-358 of human TG produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7038
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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