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TGFBR2 Mouse anti-Human, Clone: OTI4F3, lyophilized, TrueMAB™

Product Code. 17679631
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Quantity:
100 μg
Unit Size:
100µg
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17679631 100 μg 100µg
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Product Code. 17679631 Supplier Origene Technologies Supplier No. CF808048

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Specifications

Antigen TGFBR2
Applications Western Blot
Classification Monoclonal
Clone OTI4F3
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene TGFBR2
Gene Accession No. P37173
Gene Alias AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII
Gene Symbols TGFBR2
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 23-294 of human TGFBR2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7048
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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