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Invitrogen™ TGIF Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA566463

Product Code. 15939164

  • € 586.00 / 100µL

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This item is not returnable. View return policy

Description

Description

Immunogen sequence: SVLARPSVICH TTVTALKDVP FSLCQSVGVG QNTDIQQIAA KNFTDTSLMY PEDTCKSGPS TNTQ Highest antigen sequence identity to the following orthologs - mouse 82%, rat 77%.

TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TGIF
Polyclonal
Unconjugated
TGIF1
5'-TG-3'-interacting factor 1; AA959811; AI462167; Homeobox protein TGIF1; HPE4; TALE family homeobox; TALE homeobox TG-interacting factor; Tfig; TG interacting factor 1; TGFB induced factor homeobox 1; TGFB-induced factor homeobox 1; TGIF; Tgif1; transforming growth factor-beta-induced factor
Rabbit
Antigen affinity chromatography
RUO
7050
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ChIP Assay, Western Blot, Immunocytochemistry
0.05 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q15583
TGIF1
Recombinant Human TGIF. Recombinant protein control fragment (Product #RP-105224).
100 μL
Primary
Human
Antibody
IgG
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