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Thyroglobulin Antibody (6E1), Alexa Fluor™ 532, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-33096AF532

Product Code. 18134274

  • € 533.00 / 0.10mL

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Description

Description

Thyroglobulin Monoclonal specifically detects Thyroglobulin in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Thyroglobulin
Monoclonal
Alexa Fluor 532
50 mM sodium borate with 0.05% sodium azide
TG
Thyroglobulin isolated from human thyroid glands was used as the immunogen for the antibody.
0.1 mL
Primary
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Store at 4°C in the dark.
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
60
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
AITD3TGN, TDH3, Tg, thyroglobulin
Mouse
Protein A or G purified
Cancer, Cell Biology
7038.0
Human, Mouse, Rat
IgG1 κ
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