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Thyroglobulin Antibody (TGB04 + TGB05), Allophycocyanin, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-34724APC

Product Code. 18122109

  • € 544.00 / 0.10mL

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Description

Description

Thyroglobulin Monoclonal specifically detects Thyroglobulin in Human, Mouse, Rat samples. It is validated for Flow Cytometry.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Thyroglobulin
Monoclonal
APC
AITD3TGN, TDH3, Tg, thyroglobulin
Mouse
660 kDa
0.1 mL
Cancer, Cell Biology
7038
Human, Mouse, Rat
Purified
Flow Cytometry
TGB04 + TGB05
Flow Cytometry
TG
Human thyroid follicular cells
Protein A or G purified
RUO
Primary
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Store at 4C in the dark.
IgG1 κ
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