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Invitrogen™ Thyroglobulin Monoclonal Antibody (TG60), Invitrogen™

Product Code. 17820176
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17820176 100 μg 100µg
11538882 500 μg 1mg
17890476 1 mg 1mg
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Product Code. 17820176 Supplier Invitrogen™ Supplier No. MA546102

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Description

Mouse Monoclonal Antibody

MA1-10593 detects Thyroglobulin, specifically both T3 and T4, from human samples. MA1-10593 has been successfully used in ELISA applications. The MA1-10593 immunogen is purified human Thyroglobulin.

The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thyroglobulin
Applications ELISA
Classification Monoclonal
Clone TG60
Concentration 2.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene TG
Gene Accession No. P01266
Gene Alias AITD3; cog; Colloid; congenital goiter; hereditary goitre; TG; Tgn; thyroglobulin; thyroglobulin precursor
Gene Symbols TG
Host Species Mouse
Immunogen Purified human Thyroglobulin.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7038
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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