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TIM-4 Rat anti-Mouse, PE, Clone: 54 (RMT4-54), eBioscience™

Rat Monoclonal Antibody

Merk:  Affymetrix eBioscience 12-5866-82

Overige gegevens : Gewicht : 0.25000kg

 Bekijk meerdere types van dit product via de

Produktcode. 15248859

  • € 270.00 / 100 µg


Geschatte verzenddatum
bij leverancier 24-12-2019
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Beschrijving

Beschrijving

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
Specificatie

Specificatie

TIM-4
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q6U7R4
SMUCKLER, TIM4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell membrane protein 4; TIM-4; TIMD-4
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
54 (RMT4-54)
PE
Timd4
Liquid
Timd4
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
276891
Video's
Documentatie

For Research Use Only.