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TOKU-E™ Timentin ReadyMade™ Solution

Product Code. 30044052
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Quantity:
10 x 1 mL
Unit Size:
10mL
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Product Code. 30044052

Brand: TOKU-E™ T14710x1ML

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Description

Timentin ReadyMade™ Solution is provided as a sterile-filtered solution of Timentin (Ticarcillin Disodium with Clavulanate Potassium 15:1) in water.

  • CAS Number: 116876-37-0
  • Molecular Formula: C15H14N2Na2O6S2 / C8H8KNO5
  • Molecular Weight: 665.64 g/mol (combined)
  • Storage Conditions: -20°C
  • Form: Liquid
  • Source: Semi-synthetic
  • Spectrum: Timentin is broad-spectrum and has activity against Gram-negative cocci other than enterococci and methicillin-resistant staphylococci; Enterobacteriaceae, including drug-resistant strains; and anaerobes
  • Mechanism of Action: Timentin interferes with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Clavulanic acid is a 'suicide' or 'mechanism based' β-lactamase inhibitor. Clavulanic acid contains a β-lactam ring that binds strongly to β-lactamase at or near its activation site, thereby permanently inhibiting enzymatic activity. This action protects other beta-lactam antibiotics (penicillins, cephalosporins, etc.) from β-lactamase catalysis, thereby enhancing their antibacterial activity

Specifications

Chemical Name or Material Ticarcillin Disodium with Clavulanate Potassium 15:1
Physical Form Liquid
CAS 116876-37-0
Source Semi-synthetic
Packaging 2 mL plastic vial
Sterile Filtered Yes, 0.22 μm
Sterility Sterile
Color Colorless
Concentration 95 to 105 mg/mL
Quantity 10 x 1 mL
Purity Grade Notes >90% (HPLC)
Assay Percent Range >75% Ticarcillin DiNa, >5% Clavulanate
Assay Percent Notes Timentin, Dried Basis
Molecular Formula C15H14N2Na2O6S2 / C8H8KNO5
Product Line ReadyMade™ Solutions
Shipping Condition Ice Pack
Synonym Ticarcillin Disodium Salt/ Potassium Clavulanate mixture (15:1)
Molecular Weight (g/mol) 665.64 g/mol
Formula Weight 665.64 amu
Percent Purity >90%
Grade Antibiotic
Concentration or Composition (by Analyte or Components) Timentin 10%
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