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Invitrogen™ TIMM44 Recombinant Rabbit Monoclonal Antibody (8J1F10)
Description
Immunogen Sequence: WCRCPRRCLG SGIQFLSSHN LPHGSTYQMR RPGGELPLSK SYSSGNRKGF LSGLLDNVKQ ELAKNKEMKE SIKKFRDEAR RLEESDVLQE ARRKYKTIES ETVRTSEVLR KKLGELTGTV KESLHEVSKS DLGRKIKEGV EEAAKTAKQS AESVSKGGEK LGRTAAFRAL SQGVESVKKE IDDSVLGQTG PYRRPQRLRK RTEFAGDKFK EEKVFEPNEE ALGVVLHKDS K.
This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.
Specifications
Specifications
| Antigen | TIMM44 |
| Applications | ELISA, Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 8J1F10 |
| Concentration | 2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | TIMM44 |
| Gene Accession No. | O35094, O43615 |
| Gene Alias | 0710005E20Rik; D8Ertd118e; Mimt44; Mitochondrial import inner membrane translocase subunit TIM44; Tim44; TIMM44; translocase of inner mitochondrial membrane 44; translocase of inner mitochondrial membrane 44 homolog; translocase of inner mitochondrial membrane 44 homolog (yeast); translocator of inner mitochondrial membrane 44; translocator of inner mitochondrial membrane 44; DNA segment, Chr 8, ERATO Doi 118, expressed |
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