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Invitrogen™ TIS11D Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5101115
This item is not returnable.
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Description
Antibody detects endogenous levels of total TISD.
TIS11D, also known as ZFP36LA (zinc finger protein 36, C3H type-like 2), BRF2 (butyrate response factor 2), ERF2 or RNF162C, is a 494 amino acid protein that localizes to the nucleus and contains two CSH1-type zinc fingers. Belonging to the TIS11 family of early response proteins, TIS11D is thought to function as a nuclear transcription factor that binds to 5'UUAUUUAUUU-3' core RNA sequences and may regulate growth factor-induced cellular responses. The gene encoding TIS11D maps to human chromosome 2, which houses over 1, 400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes.
Specifications
| TIS11D | |
| Polyclonal | |
| Unconjugated | |
| ZFP36L2 | |
| Brf2; Butyrate response factor 2; EGF-response factor 2; ERF2; ERF-2; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2; mRNA decay activator protein ZFP36L2; Protein TIS11D; RNF162C; TIS11D; TISD; TPA-induced sequence 11d; ZFP36 ring finger protein like 2; ZFP36 ring finger protein-like 2; ZFP36L2; ZFP36-like 2; zinc finger protein 36, C3H type-like 1; zinc finger protein 36, C3H type-like 2; zinc finger protein 36, C3H type-like 2-like; zinc finger protein 36, C3H1 type-like 2; zinc finger protein, C3H type, 36-like 2 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 12193, 678 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P23949, P47974 | |
| ZFP36L2 | |
| A synthesized peptide derived from human ZFP36L2(Accession P47974), corresponding to amino acid residues T238-P288. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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