missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ TL1A Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA520015
This item is not returnable.
View return policy
Description
This antibody will not cross-react with TL1. A suggested positive control is PC-3 cell lysate. PA5-20015 can be used with blocking peptide PEP-0134.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined.
Specifications
| TL1A | |
| Polyclonal | |
| Unconjugated | |
| TNFSF15 | |
| bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15); MGC129934; MGC129935; TL1; TL1A; TNF ligand-related molecule 1; TNF superfamily ligand TL1A; TNFSF15; TNLG1B; tumor necrosis factor (ligand) superfamily member 15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand 1B; tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form; tumor necrosis factor superfamily member 15; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor; vascular endothelial growth inhibitor-192A; Vegi; VEGI192A | |
| Rabbit | |
| Ion-exchange chromatography | |
| RUO | |
| 252878, 326623, 9966 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| O95150, Q5UBV8, Q8K3Y7 | |
| TNFSF15 | |
| A peptide corresponding to 14 amino acids near the N terminus of human TL1A. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction