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Invitrogen™ TLX Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA540484

Product Code. 15584182

  • € 518.00 / 100µL

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Description

Description

Peptide sequence: MSKPAGSTSR ILDIPCKVCG DRSSGKHYGV YACDGCSGFF KRSIRRNRTY Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Nuclear receptor TLX, a NR2 hepatocyte NF4-like receptor, has been shown to affect anterior brain differentiation, retinal development, and vision. It has been suggested that TLX targets genes for RAR beta2 and Pax2 during retinal development. Homozygous TLX mutant mice are viable at birth but exhibit reduced forebrain development and are more aggressive than wild-type mice. Mice with deleted TLX locus exhibit cerebral hypoplasia, blindness, and extreme aggression (fierce (frc) phenotype). TLX expression has been documented in mouse brain and eye. ESTs have been isolated from normal human brain libraries.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TLX
Polyclonal
Unconjugated
NR2E1
fc30e03; fc39f12; fierce; frc; HTll; Mtl1; Mtll; NR2D1; nr2e1; Nuclear receptor subfamily 2 group E member 1; nuclear receptor subfamily 2, group E, member 1; nuclear receptor TLX; Protein tailless homolog; tailes-related receptor; tailless; tailless homolog; TLL; Tlx; wu:fc30e03; wu:fc39f12; XTLL; zgc:100991
Rabbit
Affinity chromatography
RUO
7101
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry, Western Blot
0.5 mg/mL
PBS with 2% sucrose and 0.09% sodium azide
Q9Y466
NR2E1
Synthetic peptide directed towards the N-terminal of human NR2E1 (aa 1-50).
100 μL
Primary
Human
Antibody
IgG
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