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Invitrogen™ TMED5 Polyclonal Antibody
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Product Code. 17949712
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Quantity:
100 μL
Unit Size:
100µL
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17949712 100 μL 100µL
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Product Code. 17949712 Supplier Invitrogen™ Supplier No. PA5144635

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Description

Rabbit Polyclonal Antibody

Positive control: Rat liver tissue lysate, A431 cell lysate, Jurkat cell lysate, Hela cell lysate, SiHa cell lysate, rat bladder tissue, mouse large intestine tissue. Predicted band size: 26 kDa Subcellular Location: Cis-Golgi network membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane.

The TMED5 gene encodes the transmembrane emp24 domain-containing protein 5, a member of the TMED family, which is involved in intracellular protein trafficking. This family is essential for the transport of proteins between the endoplasmic reticulum and the Golgi apparatus. TMED5 is a member of the γ subfamily and has been shown to regulate vital cellular processes, including protein secretion and signal transduction. Dysregulation of TMED5 has been implicated in various diseases, including hepatocellular carcinoma (HCC). Increased expression of TMED5 mRNA in HCC tissues is associated with poorer overall survival rates compared to normal tissues, suggesting its role in tumor progression and metastasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMED5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene TMED5
Gene Accession No. Q6AXN3, Q9CXE7, Q9Y3A6
Gene Alias CGI-100; p24 family protein gamma-2; p24g2; p24gamma2; p28; TMED5; Transmembrane emp24 domain-containing protein 5; transmembrane emp24 protein transport domain containing 5; transmembrane p24 trafficking protein 5; UNQ397/PRO733
Gene Symbols TMED5
Host Species Rabbit
Immunogen Recombinant protein within Human TMED5 aa 1-200/229.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 289883, 50999, 73130
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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