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Invitrogen™ TMEM16B Polyclonal Antibody
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Product Code. 16311305
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Quantity:
100 μL
Unit Size:
100µL
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16311305 100 μL 100µL
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Product Code. 16311305 Supplier Invitrogen™ Supplier No. PA584348

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EPVSLEARLS RMHFHDSQRK VDYVLAYHYR KRGVHLAQGF PGHSLAIVSN GETGKEPHAG GPGDIELGPL DALEEERKEQ REEFEHNLM Highest antigen sequence indentity to the following orthologs: Mouse - 84%, Rat - 85%.

Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM16B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ano2
Gene Accession No. Q9NQ90
Gene Alias ANO2; anoctamin 2; anoctamin 2 isoform Adelta4; anoctamin 2 isoform Bdelta4; anoctamin 2, calcium activated chloride channel; anoctamin 2-like; anoctamin-2; BC033409; C12orf3; LOC100361584; Tmem16b; Transmembrane protein 16B; transmembrane protein 16B (eight membrane-spanning domains)
Gene Symbols Ano2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ANO2. Recombinant protein control fragment (Product #RP-108423).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57101
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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