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TNF-alpha Mouse, Clone: TNF706 + P/T2, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-34304-0.02MG
This item is not returnable.
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Description
TNF-alpha Monoclonal specifically detects TNF-alpha in Human, Mouse, Rat, Canine, Feline, Rabbit, Zebrafish samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications
| TNF-alpha | |
| Monoclonal | |
| Unconjugated | |
| PBS with 0.05% BSA. with 0.05% Sodium Azide | |
| APC1 protein, Cachectin, DIF, TNF, monocyte-derived, TNF-a, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha | |
| Mouse | |
| 17 kDa | |
| 0.02 mg | |
| Adaptive Immunity, Asthma, Autophagy, Biologically Active Proteins, Cancer, Cytokine Research, Diabetes Research, Immune System Diseases, Immunology, Innate Immunity | |
| 7124 | |
| Human, Mouse, Rat, Canine, Feline, Rabbit, Zebrafish | |
| Purified |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen) | |
| TNF706 + P/T2 | |
| Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 1-2ug/ml, Immunohistochemistry-Frozen 1-2ug/ml | |
| P01375 | |
| TNF | |
| Recombinant human TNF-alpha (TNF706); A hexadecapeptide corresponding to aa115-130 of human TNF-alpha, conjugated to thyroglobulin (P/T2) | |
| Protein A purified | |
| RUO | |
| Primary | |
| TNF alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17kDa band following SDS PAGE under non-reducing conditions. TNF alpha causes cytolysis of certain transformed cells. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex. | |
| Store at 4C. | |
| IgM |
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