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Invitrogen™ TNFRSF11B Monoclonal Antibody (9C2)

Description
Positive Control: K562, rat lung tissue, human liver tissue, human small intestine tissue, mouse heart tissue.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Specifications
Specifications
| Antigen | TNFRSF11B |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 9C2 |
| Concentration | 2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 |
| Gene | TNFRSF11B |
| Gene Accession No. | O00300 |
| Gene Alias | LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) |
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