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Invitrogen™ Human TNFRSF18 (GITR) ELISA Kit

Product Code. 17798033
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Quantity:
10 x 96 Tests
Unit Size:
Pack of 10
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17798033 10 x 96 Tests Pack of 10
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Product Code. 17798033 Supplier Invitrogen™ Supplier No. EHTNFRSF18X10

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Description

ELISA

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9Y5U5
Assay Range 13.7 to 10,000 pg/mL
Assay Sensitivity 15 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 8784
Gene Symbol Tnfrsf18
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 10 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 100 μL
Storage Requirements 2°C to 8°C
Target GITR
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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