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Invitrogen™ TOB1 Polyclonal Antibody
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Product Code. 30535818
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
30535818 100 μg 100µg
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Product Code. 30535818 Supplier Invitrogen™ Supplier No. PA5148982

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Description

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOB1
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene TOB1
Gene Accession No. P50616
Gene Alias APRO5; APRO6; MGC104792; MGC34446; PIG49; proliferation-inducing gene 49; protein Tob1; Protein Tob1-like protein; TOB; TOB1; transducer of erbB2; Transducer of erbB-2 1; transducer of ERBB2, 1; transducer of ErbB-2.1; Trob; TROB1; Unknown (protein for MGC:134447)
Gene Symbols TOB1
Host Species Goat
Immunogen E. coli-derived recombinant human TOB1, Met1-Asn345.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10140
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG
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