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Toceranib phosphate, MedChemExpress

Product Code. 16480197
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Product Code. 16480197 Supplier Medchem Express Supplier No. HY10330A

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Description

MedChemExpress Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors .

Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors .

Specifications

Chemical Name or Material Toceranib phosphate
CAS 874819-74-6
Color Orange
Purity Grade Notes Research
Molecular Formula C22H28FN4O6P
Quantity 50 mg
Synonym SU11654 phosphatePHA 291639E phosphate
Solubility Information DMSO : 2.46 mg/mL (4.98 mM; Need ultrasonic and warming) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C\3C=C(C=C4)F)=O)=C2C)C.O=P(O)(O)O
Molecular Weight (g/mol) 494.45
Formula Weight 494.45
Percent Purity 98.02%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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