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Invitrogen™ Tocilizumab Humanized Recombinant Human Monoclonal Antibody
Human Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA542298
This item is not returnable.
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Description
Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann-La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.
Specifications
| Tocilizumab Humanized | |
| Recombinant Monoclonal | |
| Unconjugated | |
| Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533 | |
| IL-6R. | |
| 100 μg | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid | |
| Chemical |
| ELISA, SDS-Page | |
| 2.05 mg/mL | |
| PBS with no preservative; pH 7.4 | |
| Human | |
| Protein A/G | |
| RUO | |
| Human | |
| Antibody | |
| IgG1 |
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