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Invitrogen™ TOLLIP Monoclonal Antibody (SB40a)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA528676
This item is not returnable.
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Description
TOLLIP Monoclonal Antibody for Western Blot, ICC/IF, Flow, ELISA
Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.
Specifications
| TOLLIP | |
| Monoclonal | |
| 0.5 mg/mL | |
| BBS with no preservative; pH 8.2 | |
| Q9H0E2, Q9QZ06 | |
| TOLLIP | |
| Recombinant Tollip. | |
| 200 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG2a κ |
| ELISA, Flow Cytometry, Western Blot, Immunocytochemistry | |
| SB40a | |
| Unconjugated | |
| TOLLIP | |
| 4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312 | |
| Mouse | |
| Purified | |
| RUO | |
| 54472, 54473 | |
| 4°C | |
| Liquid |
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