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Invitrogen™ TOLLIP Polyclonal Antibody
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Product Code. 11576201
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Quantity:
100 μL
Unit Size:
100µL
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11576201 100 μL 100µL
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Product Code. 11576201 Supplier Invitrogen™ Supplier No. PA517384

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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOLLIP
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene TOLLIP
Gene Accession No. Q9H0E2
Gene Alias 4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312
Gene Symbols TOLLIP
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues surrounding cysteine 229 of human Tollip.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54472
Target Species Human, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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