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TOP2A Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA516322
This item is not returnable.
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Description
PA5-16322 targets Topoisomerase II alpha in IF, IHC, IP, and WB applications and shows reactivity with Human samples. The PA5-16322 immunogen is a synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIalpha.
Topo II alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2 and M-phases in transformed and developmentally regulated normal cellsTopo II alpha is also implicated in drug resistance of tumor cells.
Specifications
| TOP2A | |
| Polyclonal | |
| Unconjugated | |
| TOP2A | |
| DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha-like protein; DNA Topoisomerase II alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; EC 5.99.1.3; OTTHUMP00000207108; P11388-1; TOP2; Top-2; Top2a; TOPOII; topoisomerase (DNA) 2 alpha; topoisomerase (DNA) II alpha; topoisomerase (DNA) II alpha 170kDa; topoisomerase ii alpha; topoisomersae II; TP2A | |
| Rabbit | |
| Protein A | |
| RUO | |
| 7153 | |
| 4° C | |
| Liquid |
| Immunohistochemistry, Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P11388 | |
| TOP2A | |
| A synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIalpha | |
| 500 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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