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Tocris Bioscience™ Topiramate
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Product Code. 18063982
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18063982

Brand: Tocris Bioscience™ 3620/50

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This item is not returnable. View return policy

Description

GluR5 antagonist; inhibits carbonic anhydrase (CA) II and IV

Topiramate is an anticonvulsant. Antagonizes GluK1 (formerly GluR5) kainate receptors (IC50 = 0.46 μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels. Also inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2 μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

TRUSTED_SUSTAINABILITY

Specifications

Quantity 50 mg
Product Type Topiramate
Purity >99%
Molecular Weight (g/mol) 339.36
Inhibitors Topiramate

For Research Use Only

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