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Invitrogen™ TORC2 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5142679
This item is not returnable.
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Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions. Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP. CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus. Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.
Specifications
| TORC2 | |
| Polyclonal | |
| Unconjugated | |
| CRTC2 | |
| 4632407F12Rik; CREB regulated transcription coactivator 2; CREB-regulated transcription coactivator 2; CRTC2; mTORC2; OTTHUMP00000035255; RGD1308903; TORC2; TORC-2; transducer of CREB protein 2; transducer of regulated cAMP response element-binding protein (CREB) 2; transducer of regulated cAMP response element-binding protein 2 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 200186, 310615 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q3LRZ1, Q53ET0 | |
| CRTC2 | |
| Peptide with sequence C-DPAVEDSFRSDRLQ (aa 679-692). | |
| 100 μg | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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