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TP53BP1 Mouse anti-Human, Clone: OTI12D4, lyophilized, TrueMAB™

Product Code. 17619151
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
17619151 100 μg 100µg
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Product Code. 17619151 Supplier Origene Technologies Supplier No. CF807151

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.

Specifications

Antigen TP53BP1
Applications Western Blot
Classification Monoclonal
Clone OTI12D4
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene TP53BP1
Gene Accession No. Q12888
Gene Alias 53BP1, TDRD30, TP53, p202, p53BP1
Gene Symbols TP53BP1
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-300 of human TP53BP1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7158
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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