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Invitrogen™ TP53I11 Polyclonal Antibody

Description
Immunogen sequence: MAAKQPPPLM KKHSQTDLVS RLKTRKILGV GGEDDDGEVH RSKISQVLGN EIKFTIREPL GLRVWQFVSA; Positive Samples: HeLa, Mouse brain; Cellular Location: Membrane, Multi-pass membrane protein.
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Specifications
Specifications
| Antigen | TP53I11 |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 2.69 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | TP53I11 |
| Gene Accession No. | B3DMA0, O14683 |
| Gene Alias | p53-induced gene 11 protein; Pig11; TP53I11; transformation related protein 53 inducible protein 11; Trp53i11; tumor protein p53 inducible protein 11; tumor protein p53-inducible protein 11 |
| Gene Symbols | TP53I11 |
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