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Invitrogen™ TPCN2 Polyclonal Antibody
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Product Code. 17816642
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Quantity:
100 μg
Unit Size:
100µL
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Product Code. Quantity unitSize
17816642 100 μg 100µL
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Product Code. 17816642 Supplier Invitrogen™ Supplier No. PA5142504

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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Tpcn2 is a nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. Tpcn2 may also be involved in smooth muscle contraction. The Tpcn2 gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The Tpcn2 protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. Tpcn2 is a ubiquitously expressed gene that has elevated expression in liver and kidney. Two common nonsynonymous SNPs in the Tpcn2 gene strongly associate with blond versus brown hair pigmentation. Diseases associated with TPCN2 include Deafness, Autosomal Recessive 63 and Deafness, Autosomal Recessive 7.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPCN2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene TPCN2
Gene Accession No. Q8NHX9
Gene Alias BC025890; D830047E22Rik; SHEP10; Tpc2; TPCN2; Two pore calcium channel protein 2; two pore segment channel 2; two-pore calcium channel protein 2; voltage-dependent calcium channel protein TPC2
Gene Symbols TPCN2
Host Species Goat
Immunogen Peptide with sequence C-EDELTERLSQHPH (aa 735-747).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 219931
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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