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Invitrogen™ TRABD2B Polyclonal Antibody

Description
Reconstitute at 0.2 mg/mL in sterile PBS.
TRABD2B (TraB Domain Containing 2B) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include metalloendopeptidase activity and Wnt-protein binding. An important paralog of this gene is TRABD2A. Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Specifications
Specifications
| Antigen | TRABD2B |
| Applications | Flow Cytometry, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with trehalose and no preservative |
| Gene | TRABD2B |
| Gene Accession No. | A6NFA1 |
| Gene Alias | TIKI2; UPF0632 Protein A |
| Gene Symbols | TRABD2B |
| Show More |
Product Title
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