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Invitrogen™ TRABD2B Polyclonal Antibody

Sheep Polyclonal Antibody
Brand: Invitrogen™ PA5148511
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
TRABD2B (TraB Domain Containing 2B) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include metalloendopeptidase activity and Wnt-protein binding. An important paralog of this gene is TRABD2A. Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Specifications
| TRABD2B | |
| Polyclonal | |
| Unconjugated | |
| TRABD2B | |
| TIKI2; UPF0632 Protein A | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 388630 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Flow Cytometry, Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| A6NFA1 | |
| TRABD2B | |
| Human embryonic kidney cell line HEK293-derived transfected with human Tiki2/TRABD2B. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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