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Invitrogen™ TRAC-1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA590267
This item is not returnable.
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Description
Positive Samples: Mouse testis Immunogen sequence: LEVLHQPVRT RCGHVFCRSC IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMKSEYKNC AECDTLVCLS EMRAHIRTCQ KYIDKYGPLQ ELEETAARCV CPFCQRELYE DSLLDHCITH HRSERRPVFC PLCRLIPDEN PSSFSGSLIR HLQVSHTLFY.
TRAC-1 is a 232 amino acid protein containing an N-terminal RING-type zinc finger domain. It functions as a positive regulator in the T-cell receptor signaling pathway, thus leading to T-cell activation. It mediates ubiquitination and subsequent proteasomal degradation of target proteins. TRAC-1 is expressed in lymphoid tissues, including bone marrow, spleen, thymus as well as in other tissues. It is predominantly expressed in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells.
Specifications
| TRAC-1 | |
| Polyclonal | |
| Unconjugated | |
| RNF125 | |
| 4930553F04Rik; E3 ubiquitin-protein ligase RNF125; RING finger protein 125; ring finger protein 125, E3 ubiquitin protein ligase; RNF125; T-cell RING activation protein 1; T-cell ring protein identified in activation screen; TNORS; TRAC1; TRAC-1 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 54941 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 2.32 mg/mL | |
| PBS with 50% glycerol and 0.09% sodium azide; pH 7.3 | |
| Q96EQ8 | |
| RNF125 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 41-200 of human RNF125 (NP_0603012). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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