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Invitrogen™ TRAIL-R4 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA589612
This item is not returnable.
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Description
Immunogen sequence: VLFRRRSCPS RVPGAEDNAR NETLSNRYLQ PTQVSEQEIQ GQELAELTGV TVELPEEPQR LLEQAEAEGC QRRRLLVPVN DADSADISTL LDASATLEEG HAKETIQDQL VGSEKLFYEE DEAGSATSCL; Positive Samples: 22Rv1, Rat testis; Cellular Location: Membrane, Single-pass type I membrane protein.
TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.
Specifications
| TRAIL-R4 | |
| Polyclonal | |
| Unconjugated | |
| TNFRSF10D | |
| CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; UNQ251/PRO288 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 8793 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 0.78 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q9UBN6 | |
| TNFRSF10D | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 257-386 of human TNFRSF10D (NP_0038312). | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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