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Invitrogen™ TRAM2 Polyclonal Antibody

Description
TRAM2 Polyclonal Antibody for Western Blot, IHC (P)
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
Specifications
Specifications
| Antigen | TRAM2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.09% sodium azide; pH 7.4 |
| Gene | TRAM2 |
| Gene Accession No. | Q15035 |
| Gene Alias | C330003D03Rik; KIAA0057; LOC100361830; tram2; TRAM-like protein; Translocating chain-associated membrane protein 2; translocating chain-associating membrane protein 2; translocation associated membrane protein 2; wu:fb20c11; wu:fi23a12; zgc:111902; zgc:55869; zgc:76937 |
| Gene Symbols | TRAM2 |
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