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Invitrogen™ Transferrin Receptor Monoclonal Antibody (R17217.1.4), PE
Rat Monoclonal Antibody
Brand: Invitrogen™ MA517923
This item is not returnable.
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Description
Transferrin Receptor Monoclonal Antibody for Flow
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
Specifications
| Transferrin Receptor | |
| Monoclonal | |
| 0.1 mg/mL | |
| PBS with 4-5mg/mL BSA and 0.02% sodium azide | |
| Q62351 | |
| TFRC | |
| Induced Friend Erythroleukemia 745.6 cell extracts. | |
| 50 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Flow Cytometry | |
| R17217.1.4 | |
| PE | |
| TFRC | |
| 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr | |
| Rat | |
| Protein G | |
| RUO | |
| 22042 | |
| 4°C, do not freeze | |
| Liquid |
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