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Invitrogen™ Transferrin Receptor Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583022

Product Code. 16319984

  • € 586.00 / 100µL

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Description

Description

Immunogen sequence: KTECERLAGT ESPVREEPGE DFPAARRLYW DDLKRKLSEK LDSTDFTGTI KLLNENSYVP REAGSQKDEN LALYVENQFR EFKLSKV Highest antigen sequence indentity to the following orthologs: Mouse - 61%, Rat - 57%.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Transferrin Receptor
Polyclonal
Unconjugated
TFRC
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Rabbit
Antigen affinity chromatography
RUO
7037
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.20 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P02786
TFRC
Recombinant protein corresponding to Human TFRC.
100 μL
Primary
Human
Antibody
IgG
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