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Invitrogen™ Transferrin Receptor Polyclonal Antibody
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Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5143016

Product Code. 17897632

  • € 465.00 / 100µg

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This item is not returnable. View return policy

Description

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Transferrin Receptor
Polyclonal
Unconjugated
TFRC
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Goat
Ammonium sulfate precipitation
RUO
7037
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
P02786
TFRC
Peptide with sequence TRFSLARQVDGDNSH-C (aa 21-35).
100 μg
Primary
Human
Antibody
IgG
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