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  6. Transgelin 2 Mouse anti-Human, Mouse, Clone: 2E5G1, Proteintech

Transgelin 2 Mouse anti-Human, Mouse, Clone: 2E5G1, Proteintech

Product Code. 16846995 Shop All Proteintech Products
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150 μL
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20µL
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16846995 150 μL 150µL
16856995 20 μL 20µL
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Product Code. 16846995 Supplier Proteintech Supplier No. 600441IG150UL

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Description

Mouse Monoclonal Antibody

Our test results showed that this antibody Is specific to TAGLN2. It does not bind TAGLN1 and TAGLN3.

Transgelin (also designated SM22alpha), is expressed abundantly in smooth muscle cells. Transgelin-2 (also known as SM22alpha homolog) is a homolog of transgelin and is also expressed in smooth muscle cells and by peritoneal B-1 cells. The human transgelin-2 gene (designated TAGLN2), which is located on chromosome 1q231-q25, encodes a 199 amino acid protein that contains a calponin-like repeat and a calponin-homology (CH) domain. Transgelin-2 may function very similarly to transgelin. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is downregulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds actin, causing actin fibers to gel within minutes of binding. Binding of transgelin to actin occurs at a ratio of 1:6 actin monomers.

Specifications

Antigen Transgelin 2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 2E5G1
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TAGLN2
Gene Accession No. P37802, Q9WVA4
Gene Alias SM22 beta, SM22beta, TAGLN2, Transgelin 2, Transgelin 2/TAGLN2
Gene Symbols TAGLN2
Host Species Mouse
Immunogen Transgelin 2 Fusion Protein Ag0337
Purification Method Caprylic Acid Precipitation
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21346, 8407
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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